학술논문

The Role of Peptide Hormones Discovered in the 21st Century in the Regulation of Adipose Tissue Functions
Document Type
article
Source
Genes, Vol 12, Iss 5, p 756 (2021)
Subject
adropin
apelin and elabela
irisin
kisspeptin
MOTS-c
phoenixin
Genetics
QH426-470
Language
English
ISSN
2073-4425
Abstract
Peptide hormones play a prominent role in controlling energy homeostasis and metabolism. They have been implicated in controlling appetite, the function of the gastrointestinal and cardiovascular systems, energy expenditure, and reproduction. Furthermore, there is growing evidence indicating that peptide hormones and their receptors contribute to energy homeostasis regulation by interacting with white and brown adipose tissue. In this article, we review and discuss the literature addressing the role of selected peptide hormones discovered in the 21st century (adropin, apelin, elabela, irisin, kisspeptin, MOTS-c, phoenixin, spexin, and neuropeptides B and W) in controlling white and brown adipogenesis. Furthermore, we elaborate how these hormones control adipose tissue functions in vitro and in vivo.