학술논문
Sarcoma classification by DNA methylation profiling
Document Type
article
Author
Christian Koelsche; Daniel Schrimpf; Damian Stichel; Martin Sill; Felix Sahm; David E. Reuss; Mirjam Blattner; Barbara Worst; Christoph E. Heilig; Katja Beck; Peter Horak; Simon Kreutzfeldt; Elke Paff; Sebastian Stark; Pascal Johann; Florian Selt; Jonas Ecker; Dominik Sturm; Kristian W. Pajtler; Annekathrin Reinhardt; Annika K. Wefers; Philipp Sievers; Azadeh Ebrahimi; Abigail Suwala; Francisco Fernández-Klett; Belén Casalini; Andrey Korshunov; Volker Hovestadt; Felix K. F. Kommoss; Mark Kriegsmann; Matthias Schick; Melanie Bewerunge-Hudler; Till Milde; Olaf Witt; Andreas E. Kulozik; Marcel Kool; Laura Romero-Pérez; Thomas G. P. Grünewald; Thomas Kirchner; Wolfgang Wick; Michael Platten; Andreas Unterberg; Matthias Uhl; Amir Abdollahi; Jürgen Debus; Burkhard Lehner; Christian Thomas; Martin Hasselblatt; Werner Paulus; Christian Hartmann; Ori Staszewski; Marco Prinz; Jürgen Hench; Stephan Frank; Yvonne M. H. Versleijen-Jonkers; Marije E. Weidema; Thomas Mentzel; Klaus Griewank; Enrique de Álava; Juan Díaz Martín; Miguel A. Idoate Gastearena; Kenneth Tou-En Chang; Sharon Yin Yee Low; Adrian Cuevas-Bourdier; Michel Mittelbronn; Martin Mynarek; Stefan Rutkowski; Ulrich Schüller; Viktor F. Mautner; Jens Schittenhelm; Jonathan Serrano; Matija Snuderl; Reinhard Büttner; Thomas Klingebiel; Rolf Buslei; Manfred Gessler; Pieter Wesseling; Winand N. M. Dinjens; Sebastian Brandner; Zane Jaunmuktane; Iben Lyskjær; Peter Schirmacher; Albrecht Stenzinger; Benedikt Brors; Hanno Glimm; Christoph Heining; Oscar M. Tirado; Miguel Sáinz-Jaspeado; Jaume Mora; Javier Alonso; Xavier Garcia del Muro; Sebastian Moran; Manel Esteller; Jamal K. Benhamida; Marc Ladanyi; Eva Wardelmann; Cristina Antonescu; Adrienne Flanagan; Uta Dirksen; Peter Hohenberger; Daniel Baumhoer; Wolfgang Hartmann; Christian Vokuhl; Uta Flucke; Iver Petersen; Gunhild Mechtersheimer; David Capper; David T. W. Jones; Stefan Fröhling; Stefan M. Pfister; Andreas von Deimling
Source
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Sarcomas are morphologically heterogeneous tumours rendering their classification challenging. Here the authors developed a classifier using DNA methylation data from several soft tissue and bone sarcoma subtypes, which has the potential to improve classification for research and clinical purposes.