학술논문
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences
Document Type
article
Author
Walter Rayford; Alp Tuna Beksac; Jordan Alger; Mohammed Alshalalfa; Mohsen Ahmed; Irtaza Khan; Ugo G. Falagario; Yang Liu; Elai Davicioni; Daniel E. Spratt; Edward M. Schaeffer; Felix Y. Feng; Brandon Mahal; Paul L. Nguyen; Robert B. Den; Mark D. Greenberger; Randy Bradley; Justin M. Watson; Matthew Beamer; Lambros Stamatakis; Darrell J. Carmen; Shivanshu Awasthi; Jonathan Hwang; Rachel Weil; Harri Merisaari; Nihal Mohamed; Leslie A. Deane; Dimple Chakravarty; Kamlesh K. Yadav; Kosj Yamoah; Sujit S. Nair; Ashutosh K. Tewari
Source
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Subject
Language
English
ISSN
2399-3642
Abstract
Walter Rayford, Alp Tuna Beksac et al. investigated gene expression alterations in African-American and European-American men who underwent radical prostatectomy for prostate cancer. The observed differences include higher expression of inflammation genes and lower expression of mismatch repair genes in African-American men.