학술논문
Diagnosing primary pancreatic acinar cell carcinoma – Clinical correlation of radiological/molecular imaging, histopathologic features and whole genome/transcriptome profiling, and review of the literature
Document Type
article
Author
Source
Current Problems in Cancer: Case Reports, Vol 9, Iss , Pp 100213- (2023)
Subject
Language
English
ISSN
2666-6219
Abstract
Pancreatic acinar cell carcinoma (ACC) is a rare pancreatic neoplasm, often eluding clinicians because of the lack of diagnosis awareness and expert knowledge regarding clinical, radiological and pathological characteristics of ACC. Main differential diagnoses include pancreatic ductal adenocarcinoma (PDAC) and pancreatic neuroendocrine tumor (PNET) and accurate diagnosis is crucial to ensure optimal treatment and outcomes. This case of a 58-year old male illustrates the correlation between clinical, imaging, molecular histopathological and whole genome and transcriptome profiling that was required to diagnose and guide treatment of this complex pancreatic ACC.