학술논문

DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
Document Type
article
Source
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Here the authors identify differences in cortical DNA methylation associated with Alzheimer’s disease pathology, and profiling nuclei from specific cell-types, find that most of these differences reflect variation occurring in non-neuronal cells.