학술논문
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection
Document Type
article
Author
Benjamin M. Tang; Maryam Shojaei; Sally Teoh; Adrienne Meyers; John Ho; T. Blake Ball; Yoav Keynan; Amarnath Pisipati; Aseem Kumar; Damon P. Eisen; Kevin Lai; Mark Gillett; Rahul Santram; Robert Geffers; Jens Schreiber; Khyobeni Mozhui; Stephen Huang; Grant P. Parnell; Marek Nalos; Monika Holubova; Tracy Chew; David Booth; Anand Kumar; Anthony McLean; Klaus Schughart
Source
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
Identification of host factors associated with severe influenza infection could provide insights into treatment options. Here, the authors provide transcriptomic analyses of blood from >100 influenza infected patients and show that changes in circulating neutrophils are associated with severe influenza infection.