학술논문
The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance
Document Type
article
Author
Ian D. Ferguson; Bonell Patiño-Escobar; Sami T. Tuomivaara; Yu-Hsiu T. Lin; Matthew A. Nix; Kevin K. Leung; Corynn Kasap; Emilio Ramos; Wilson Nieves Vasquez; Alexis Talbot; Martina Hale; Akul Naik; Audrey Kishishita; Priya Choudhry; Antonia Lopez-Girona; Weili Miao; Sandy W. Wong; Jeffrey L. Wolf; Thomas G. Martin; Nina Shah; Scott Vandenberg; Sonam Prakash; Lenka Besse; Christoph Driessen; Avery D. Posey; R. Dyche Mullins; Justin Eyquem; James A. Wells; Arun P. Wiita
Source
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
The myeloma cell surface proteome regulates plasma cell biology and delineates therapy targets. Here, the authors profile the myeloma surfaceome at baseline and in drug resistance, finding the potential target CCR10, and include a streamlined approach to primary sample analysis.