학술논문

Hepcidin regulation in Kenyan children with severe malaria and non-typhoidal Salmonella bacteremia
Document Type
article
Source
Haematologica, Vol 107, Iss 7 (2021)
Subject
Diseases of the blood and blood-forming organs
RC633-647.5
Language
English
ISSN
0390-6078
1592-8721
Abstract
Malaria and invasive non-typhoidal Salmonella (NTS) are life-threatening infections that often co-exist in African children. The iron-regulatory hormone hepcidin is highly upregulated during malaria and controls the availability of iron, a critical nutrient for bacterial growth. We investigated the relationship between Plasmodium falciparum malaria and NTS bacteremia in all pediatric admissions aged