학술논문

On the Potential of Relational Databases for the Detection of Clusters of Infection and Antibiotic Resistance Patterns
Document Type
article
Source
Antibiotics, Vol 12, Iss 4, p 784 (2023)
Subject
decision support system
infectious diseases
hotspot
relational databases
Klebsiella
nosocomial diseases
Therapeutics. Pharmacology
RM1-950
Language
English
ISSN
2079-6382
Abstract
In recent years, several bacterial strains have acquired significant antibiotic resistance and can, therefore, become difficult to contain. To counteract such trends, relational databases can be a powerful tool for supporting the decision-making process. The case of Klebsiella pneumoniae diffusion in a central region of Italy was analyzed as a case study. A specific relational database is shown to provide very detailed and timely information about the spatial–temporal diffusion of the contagion, together with a clear assessment of the multidrug resistance of the strains. The analysis is particularized for both internal and external patients. Tools such as the one proposed can, therefore, be considered important elements in the identification of infection hotspots, a key ingredient of any strategy to reduce the diffusion of an infectious disease at the community level and in hospitals. These types of tools are also very valuable in the decision-making process related to antibiotic prescription and to the management of stockpiles. The application of this processing technology to viral diseases such as COVID-19 is under investigation.