학술논문

SCISSOR: a framework for identifying structural changes in RNA transcripts
Document Type
article
Source
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Many computational tools identify mRNA variations by analyzing the transformed RNA-seq data such as collapsed reads. Here, the authors report a computational method which uses shape changes in the RNA-seq coverage profile to discover changes in mRNA expression and alternative splicing.