학술논문
Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease
Document Type
article
Author
William J. Young; Jeffrey Haessler; Jan-Walter Benjamins; Linda Repetto; Jie Yao; Aaron Isaacs; Andrew R. Harper; Julia Ramirez; Sophie Garnier; Stefan van Duijvenboden; Antoine R. Baldassari; Maria Pina Concas; ThuyVy Duong; Luisa Foco; Jonas L. Isaksen; Hao Mei; Raymond Noordam; Casia Nursyifa; Anne Richmond; Meddly L. Santolalla; Colleen M. Sitlani; Negin Soroush; Sébastien Thériault; Stella Trompet; Stefanie Aeschbacher; Fariba Ahmadizar; Alvaro Alonso; Jennifer A. Brody; Archie Campbell; Adolfo Correa; Dawood Darbar; Antonio De Luca; Jean-François Deleuze; Christina Ellervik; Christian Fuchsberger; Anuj Goel; Christopher Grace; Xiuqing Guo; Torben Hansen; Susan R. Heckbert; Rebecca D. Jackson; Jan A. Kors; Maria Fernanda Lima-Costa; Allan Linneberg; Peter W. Macfarlane; Alanna C. Morrison; Pau Navarro; David J. Porteous; Peter P. Pramstaller; Alexander P. Reiner; Lorenz Risch; Ulrich Schotten; Xia Shen; Gianfranco Sinagra; Elsayed Z. Soliman; Monika Stoll; Eduardo Tarazona-Santos; Andrew Tinker; Katerina Trajanoska; Eric Villard; Helen R. Warren; Eric A. Whitsel; Kerri L. Wiggins; Dan E. Arking; Christy L. Avery; David Conen; Giorgia Girotto; Niels Grarup; Caroline Hayward; J.Wouter Jukema; Dennis O. Mook-Kanamori; Morten Salling Olesen; Sandosh Padmanabhan; Bruce M. Psaty; Cristian Pattaro; Antonio Luiz P. Ribeiro; Jerome I. Rotter; Bruno H. Stricker; Pim van der Harst; Cornelia M. van Duijn; Niek Verweij; James G. Wilson; Michele Orini; Philippe Charron; Hugh Watkins; Charles Kooperberg; Henry J. Lin; James F. Wilson; Jørgen K. Kanters; Nona Sotoodehnia; Borbala Mifsud; Pier D. Lambiase; Larisa G. Tereshchenko; Patricia B. Munroe
Source
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Subject
Language
English
ISSN
2041-1723
Abstract
The spatial and frontal QRS-T angles are electrocardiographic (ECG) predictors for arrhythmia. This work used genetic analyses to identify associated loci and pathways, and explore their relationships with other ECG traits and cardiovascular disease.