학술논문
Relation of intraventricular conduction delay to risk of new-onset heart failure and structural heart disease in the general population
Document Type
article
Author
Source
International Journal of Cardiology: Heart & Vasculature, Vol 31, Iss , Pp 100639- (2020)
Subject
Language
English
ISSN
2352-9067
Abstract
Background: Intraventricular conduction delays (IVCDs) are hallmarks of heart failure (HF) and structural heart disease (SHD) but their prognostic value for HF and SHD is unclear. Methods: Relation of eight IVCDs and the incidence of first-time HF or SHD was studied in a nationally representative random sample of 6080 Finnish subjects aged ≥ 30 years (mean age 52.1, SD 14.5 years) who participated in the health examination including 12-lead ECG. Results: During 16.5 years’ follow up, half of the subjects with left bundle branch block (LBBB) and one third of the subjects with non-specific IVCD developed HF. After controlling for known clinical risk factors the hazard ratio (HR) for new-onset HF for LBBB was 3.29 (95% confidence interval 1.93–5.63, P