학술논문
The characterization of CD8+ T-cell responses in COVID-19
Document Type
article
Author
Source
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Subject
Language
English
ISSN
22221751
2222-1751
2222-1751
Abstract
ABSTRACTThis review gives an overview of the protective role of CD8+ T cells in SARS-CoV-2 infection. The cross-reactive responses intermediated by CD8+ T cells in unexposed cohorts are described. Additionally, the relevance of resident CD8+ T cells in the upper and lower airway during infection and CD8+ T-cell responses following vaccination are discussed, including recent worrisome breakthrough infections and variants of concerns (VOCs). Lastly, we explain the correlation between CD8+ T cells and COVID-19 severity. This review aids in a deeper comprehension of the association between CD8+ T cells and SARS-CoV-2 and broadens a vision for future exploration.