학술논문

Cerebral localization of chronic myelomonocytic leukemia and improvement with high‐dose cytarabine: A case report
Document Type
article
Source
eJHaem, Vol 4, Iss 3, Pp 844-847 (2023)
Subject
case report
cerebral localization
chronic myelomonocytic leukemia
Diseases of the blood and blood-forming organs
RC633-647.5
Language
English
ISSN
2688-6146
Abstract
Abstract Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm characterized by the infiltration of blood and bone marrow by immature monocytes, in which extra‐hematopoietic localization is uncommon. We report the case of a 69‐year‐old‐man with highly likely ectopic brain CMML involvement by MRI. Without the possibility of cerebral biopsy and with a negative infectious disease assessment, high‐dose cytarabine‐based chemotherapy was successfully administered. The favorable evolution in this case highlights the potential benefit of such treatment, even without a cerebral biopsy to confirm the disease. This case can aid clinical decision‐making in the future.