학술논문

Acute Encephalopathy Associated with Influenza A Infection in Adults
Document Type
article
Source
Emerging Infectious Diseases, Vol 16, Iss 1, Pp 139-142 (2010)
Subject
Influenza A
influenza
infection
cytokine
encephalopathy
virus
Medicine
Infectious and parasitic diseases
RC109-216
Language
English
ISSN
1080-6040
1080-6059
Abstract
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.