학술논문
Integration of gene expression and DNA methylation identifies epigenetically controlled modules related to PM2.5 exposure
Document Type
article
Author
Source
Environment International, Vol 146, Iss , Pp 106248- (2021)
Subject
Language
English
ISSN
0160-4120
Abstract
Air pollution has been associated with adverse health effects across the life-course. Although underlying mechanisms are unclear, several studies suggested pollutant-induced changes in transcriptomic profiles. In this meta-analysis of transcriptome-wide association studies of 656 children and adolescents from three European cohorts participating in the MeDALL Consortium, we found two differentially expressed transcript clusters (FDR p