학술논문
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis
Document Type
article
Author
María Ercibengoa; Miguel Angel Goenaga; Carmen Ardanuy; Immaculada Grau; Cristina García-de-la-Maria; Manuel Almela; Jose María Miro; Enrique Navas; María Carmen Fariñas; Carlos Ruiz de Alegría; Javier de la Torre; Fernando Fernández; Mercedes Marín; Patricia Muñoz; Beatriz Orden; José Antonio Oteo; Lara García-Álvarez; Arístides de Alarcón; José Antonio Lepe Jiménez; Jose María Marimón
Source
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-7 (2019)
Subject
Language
English
ISSN
1471-2334
Abstract
Abstract Background Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological characteristics of S. tigurinus isolated from patients with bacteraemias, to determine the prevalence of S. tigurinus among VGS endocarditis in Spain, and to compare the clinical characteristics and outcomes of endocarditis caused by S. tigurinus and other VGS. Methods Retrospective nationwide study, performed between 2008 and 2016 in 9 Spanish hospitals from 7 different provinces comprising 237 cases of infective endocarditis. Streptococcal isolates were identified by sequencing fragments of their 16S rRNA, sodA and groEL genes. Clinical data of patients with streptococcal endocarditis were prospectively collected according to a pre-established protocol. Results Patients with endocarditis represented 7/9 (77.8%) and 26/86 (30.2%) of the bacteraemias caused by S. tigurinus and other VGS, respectively (p