학술논문
Changes in Group B Streptococcus Colonization among Pregnant Women before and after the Onset of the COVID-19 Pandemic in Brazil
Document Type
article
Author
Natália Silva Costa; André Rio-Tinto; Isabella Bittencourt Ferreira Pinto; Danielle Cristina dos Santos Silva Alvim; Amanda de Assis Rocha; Laura Maria Andrade Oliveira; Ana Caroline Nunes Botelho; Sergio Eduardo Longo Fracalanzza; Lucia Martins Teixeira; Jorge Rezende-Filho; Penélope Saldanha Marinho; Joffre Amim Júnior; Stephen Taylor; Steve Thomas; Tatiana Castro Abreu Pinto
Source
Pathogens, Vol 11, Iss 10, p 1104 (2022)
Subject
Language
English
ISSN
2076-0817
Abstract
Group B Streptococcus (GBS) is a leading cause of neonatal infections. The genitourinary and gastrointestinal tract of pregnant women are the main source of transmission to newborns. This work investigated the prevalence and characterized GBS from pregnant women in Rio de Janeiro, Brazil, comparing the periods before (January 2019 to March 2020; 521) and during (May 2020 to March 2021; 285) the COVID-19 pandemic. GBS was detected in 10.8% of anovaginal samples. Considering scenarios before and during the pandemic, GBS colonization rate significantly decreased (13.8% vs. 5.3%; p = 0.0001). No clinical and sociodemographic aspect was associated with GBS carriage (p > 0.05). A total of 80%, 13.8% and 4.6% GBS strains were non-susceptible to tetracycline, erythromycin and clindamycin, respectively. Serotype Ia was the most frequent (47.7%), followed by V (23.1%), II (18.4%), III (7.7%) and Ib (3.1%). An increasing trend of serotypes Ib and V, as well as of antimicrobial resistance rates, and a decreasing trend of serotypes II and III, were observed after the pandemic onset, albeit not statistically significant (p > 0.05). The reduction in GBS colonization rates and alterations in GBS serotypes and resistance profiles during the pandemic were not due to changes in the sociodemographic profile of the population. Considering that control and preventive measures related to the COVID-19 pandemic onset have impacted other infectious diseases, these results shed light on the need for the continuous surveillance of GBS among pregnant women in the post-pandemic era.