학술논문
County-level vaccination coverage and rates of COVID-19 cases and deaths in the United States: An ecological analysis
Document Type
article
Source
The Lancet Regional Health. Americas, Vol 9, Iss , Pp 100191- (2022)
Subject
Language
English
ISSN
2667-193X
Abstract
Summary: Background: On Dec 14, 2020, the United States initiated a nationwide COVID-19 vaccination campaign. Demonstrating clear population-level impact following vaccine introduction helps to further elucidate and quantify the public-health benefits of vaccination. Methods: Using a negative binomial regression model we evaluated the ecological association between county-level COVID-19 vaccine uptake and rates of COVID-19 cases and deaths in the United States from April 1, 2021 through October 31, 2021 controlling for a broad set of county-level environmental, sociodemographic, economic, and health-status-related characteristics. County-level data were obtained from several publicly available databases that were merged for analysis. Findings: After adjustment for county-level characteristics, US counties with ≥ 80% of their residents ≥ 12 years of age fully vaccinated against COVID-19 had 30% (95% CI: 25−35; P < .001) and 46% (38−52; P < .001) lower rates of COVID-19 cases and deaths, respectively, versus those with