학술논문
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations
Document Type
article
Author
Henry R. Kranzler; Hang Zhou; Rachel L. Kember; Rachel Vickers Smith; Amy C. Justice; Scott Damrauer; Philip S. Tsao; Derek Klarin; Aris Baras; Jeffrey Reid; John Overton; Daniel J. Rader; Zhongshan Cheng; Janet P. Tate; William C. Becker; John Concato; Ke Xu; Renato Polimanti; Hongyu Zhao; Joel Gelernter
Source
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
The genetic underpinnings of alcohol use disorder and consumption are incompletely understood. Here, the authors perform GWAS for Alcohol Use Disorder (AUD) Identification Test-Consumption scores and AUD diagnosis from electronic health records of 274,424 individuals and identify a total of 18 associated loci.