학술논문
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
Document Type
article
Author
Hou-Fu Guo; Neus Bota-Rabassedas; Masahiko Terajima; B. Leticia Rodriguez; Don L. Gibbons; Yulong Chen; Priyam Banerjee; Chi-Lin Tsai; Xiaochao Tan; Xin Liu; Jiang Yu; Michal Tokmina-Roszyk; Roma Stawikowska; Gregg B. Fields; Mitchell D. Miller; Xiaoyan Wang; Juhoon Lee; Kevin N. Dalby; Chad J. Creighton; George N. Phillips; John A. Tainer; Mitsuo Yamauchi; Jonathan M. Kurie
Source
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Subject
Language
English
ISSN
2399-3642
Abstract
Guo et al. determine the molecular basis of collagen lysyl hydroxylase 2 (LH2) substrate specificity. They further show that LH2 also functions as a collagen glucosyltransferase to promote lung cancer progression.