학술논문
Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening
Document Type
article
Author
Florian Milatz; Jens Klotsche; Martina Niewerth; Claudia Sengler; Daniel Windschall; Tilmann Kallinich; Frank Dressler; Ralf Trauzeddel; Reinhard W. Holl; Ivan Foeldvari; Normi Brück; Svenja Temming; Toni Hospach; Petra Warschburger; Rainer Berendes; Gabriele Erbis; Jasmin B. Kuemmerle-Deschner; Frank Weller-Heinemann; Johannes-Peter Haas; Annabel S. Müller-Stierlin; Agnes Mutter; Thomas Meissner; Harald Baumeister; Kirsten Minden
Source
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-13 (2024)
Subject
Language
English
ISSN
1478-6362
Abstract
Abstract Background Previous studies have shown that growing up with rheumatic conditions can fuel dissatisfaction and psychological distress, which in turn affects disease self-management and treatment adherence. Primary objective of this study was to estimate the prevalence of anxiety and depression symptoms in adolescents and young adults (AYA) with juvenile idiopathic arthritis (JIA) and to identify correlates of conspicuous screening results. Methods Initiated as part of the COACH multicenter observational study, outpatients aged 12 to 21 years participating in the National Pediatric Rheumatological Database (NPRD) were prospectively screened for mental health using the Patient Health Questionnaire-9 (PHQ-9) and the Generalised Anxiety Disorder Scale-7 (GAD-7). Results Data from 1,150 adolescents with JIA (mean age 15.6 ± 2.2 years; mean disease duration 7.2 ± 4.9 years, 69% female, 43% oligoarthritis, 26% polyarthritis) were analysed. Overall, 32.7% (n = 316) of AYA showed conspicuous screening results, of whom 30.4% reported clinically relevant suicidal or self-harm thoughts. About 19% of screened patients showed moderate to severe depressive or anxious symptoms. AYA with conspicuous screening results were older (15.8 vs. 15.2 years; p