학술논문
α-D-Glucose as a non-radioactive MRS tracer for metabolic studies of the brain
Document Type
article
Source
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract Changes in brain glucose metabolism occur in many neurological disorders as well as during aging. Most studies on the uptake of glucose in the brain use positron emission tomography, which requires injection of a radioactive tracer. Our study shows that ultra-high-field 1H-MRS can be used to measure α-d-glucose at 5.22 ppm in vivo, and the α-d-glucose can be used as a radiation-free tracer in the human brain.