학술논문
Urban environment in pregnancy and postpartum depression: An individual participant data meta-analysis of 12 European birth cohorts
Document Type
article
Author
Tim Cadman; Katrine Strandberg-Larsen; Lucinda Calas; Malina Christiansen; Iryna Culpin; Payam Dadvand; Montserrat de Castro; Maria Foraster; Serena Fossati; Mònica Guxens; Jennifer R. Harris; Manon Hillegers; Vincent Jaddoe; Yunsung Lee; Johanna Lepeule; Hanan el Marroun; Milena Maule; Rosie McEachen; Chiara Moccia; Johanna Nader; Mark Nieuwenhuijsen; Anne-Marie Nybo Andersen; Rebecca Pearson; Morris Swertz; Marina Vafeiadi; Martine Vrijheid; John Wright; Deborah A Lawlor; Marie Pedersen
Source
Environment International, Vol 185, Iss , Pp 108453- (2024)
Subject
Language
English
ISSN
0160-4120
Abstract
Background: Urban environmental exposures associate with adult depression, but it is unclear whether they are associated to postpartum depression (PPD). Objectives: We investigated associations between urban environment exposures during pregnancy and PPD. Methods: We included women with singleton deliveries to liveborn children from 12 European birth cohorts (N with minimum one exposure = 30,772, analysis N range 17,686–30,716 depending on exposure; representing 26–46 % of the 66,825 eligible women). We estimated maternal exposure during pregnancy to ambient air pollution with nitrogen dioxide (NO2) and particulate matter (PM2.5 and PM10), road traffic noise (Lden), natural spaces (Normalised Difference Vegetation Index; NDVI, proximity to major green or blue spaces) and built environment (population density, facility richness and walkability). Maternal PPD was assessed 3–18 months after birth using self-completed questionnaires. We used adjusted logistic regression models to estimate cohort-specific associations between each exposure and PPD and combined results via meta-analysis using DataSHIELD. Results: Of the 30,772 women included, 3,078 (10 %) reported having PPD. Exposure to PM10 was associated with slightly increased odds of PPD (adjusted odd ratios (OR) of 1.08 [95 % Confidence Intervals (CI): 0.99, 1.17] per inter quartile range increment of PM10) whilst associations for exposure to NO2 and PM2.5 were close to null. Exposure to high levels of road traffic noise (≥65 dB vs.