학술논문
MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis
Document Type
article
Author
Source
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Subject
Language
English
ISSN
2041-1723
Abstract
MEF2C is a transcription factor required for B-cell proliferation. Here the authors show that MEF2C is also needed in B-cell development and recovery from stress by inducing expression of DNA repair factors that prevent double stranded breaks and enable VDJ recombination.