학술논문
DNA-based platform for efficient and precisely targeted bioorthogonal catalysis in living systems
Document Type
article
Author
Source
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Copper-click reaction has been used for a wide range of bio-conjugations but does suffer from toxicity issues. Here, the authors report on the growth of copper nanoparticles on DNA with linked aptamer targeting and demonstrate high catalytic effect and improved application due to targeting and biocompatibility.