학술논문
A case-control study of the joint effect of reproductive factors and radiation treatment for first breast cancer and risk of contralateral breast cancer in the WECARE study
Document Type
article
Author
Jennifer D. Brooks; John D. Boice, Jr.; Roy E. Shore; Anne S. Reiner; Susan A. Smith; Leslie Bernstein; Julia A. Knight; Charles F. Lynch; Esther M. John; Kathleen E. Malone; Lene Mellemkjaer; Rikke Langballe; Xiaolin Liang; Meghan Woods; Marc Tischkowitz; Patrick Concannon; Daniel O. Stram; Jonine L. Bernstein
Source
Breast, Vol 54, Iss , Pp 62-69 (2020)
Subject
Language
English
ISSN
1532-3080
Abstract
Objective: To examined the impact of reproductive factors on the relationship between radiation treatment (RT) for a first breast cancer and risk of contralateral breast cancer (CBC). Methods: The Women’s Environmental Cancer and Radiation Epidemiology (WECARE) Study is a multi-center, population-based case-control study where cases are women with asynchronous CBC (N = 1521) and controls are women with unilateral breast cancer (N = 2211). Rate ratios (RR) and 95% confidence intervals (CI) were estimated using conditional logistic regression to assess the independent and joint effects of RT (ever/never and location-specific stray radiation dose to the contralateral breast [0, >0-