학술논문
Rapid Nanopore Whole-Genome Sequencing for Anthrax Emergency Preparedness
Document Type
article
Author
Heather P. McLaughlin; Julia V. Bugrysheva; Andrew B. Conley; Christopher A. Gulvik; Blake Cherney; Cari B. Kolton; Chung K. Marston; Elke Saile; Erin Swaney; David Lonsway; Amy S. Gargis; Thiphasone Kongphet-Tran; Christine Lascols; Pierre Michel; Julie Villanueva; Alex R. Hoffmaster; Jay E. Gee; David Sue
Source
Emerging Infectious Diseases, Vol 26, Iss 2, Pp 358-361 (2020)
Subject
Language
English
ISSN
1080-6040
1080-6059
1080-6059
Abstract
Human anthrax cases necessitate rapid response. We completed Bacillus anthracis nanopore whole-genome sequencing in our high-containment laboratory from a human anthrax isolate hours after receipt. The de novo assembled genome showed no evidence of known antimicrobial resistance genes or introduced plasmid(s). Same-day genomic characterization enhances public health emergency response.