학술논문
Early outcomes of kidney transplantation from elderly donors after circulatory death (GEODAS study)
Document Type
article
Author
María José Pérez-Sáez; Omar Lafuente Covarrubias; Domingo Hernández; Francesc Moreso; Edoardo Melilli; Javier Juega; Erika de Sousa; Paula López-Sánchez; María Luisa Rodríguez-Ferrero; Naroa Maruri-Kareaga; María Dolores Navarro; Rosalía Valero; María Auxiliadora Mazuecos; Francisco Llamas; Paloma Martín-Moreno; Antón Fernández-García; Jordi Espí; Carlos Jiménez; Ana Ramos; Eva Gavela; Julio Pascual; Jose M. Portolés; on behalf of the GEODAS Group
Source
BMC Nephrology, Vol 20, Iss 1, Pp 1-8 (2019)
Subject
Language
English
ISSN
1471-2369
Abstract
Abstract Background Spain has dramatically increased the number of controlled circulatory death donors (cDCD). The initial selection criteria for considering cDCD for kidney transplantation (KT) have been expanded progressively, with practically no limits in donor age during the last years. We aimed to analyze the early clinical outcomes using expanded (> 65 years) cDCD in comparison with standard ones. Methods Observational multicenter study including 19 transplant centers in Spain. We performed a systematic inclusion in a central database of every KT from expanded cDCD at each participant unit from January-2012 to January-2017. Surgical procedures and immunosuppressive protocols were based on local practices. Data was analyzed in the central office using logistic and Cox regression or competitive-risk models for multivariate analysis. Median time of follow-up was 18.1 months. Results 561 KT were performed with kidneys from cDCD, 135 from donors older than 65 years. As expected, recipients from older cDCD were also older (65.8 (SD 8.8) vs 53.7 (SD 11.4) years; p