학술논문

Association between neovascular age-related macular degeneration and dementia: a population-based case-control study in Taiwan.
Document Type
article
Source
PLoS ONE, Vol 10, Iss 3, p e0120003 (2015)
Subject
Medicine
Science
Language
English
ISSN
1932-6203
Abstract
Most available studies focusing on the association between neovascular age-related macular degeneration (AMD) and dementia have conflicting results. This study aimed to investigate the association between previously diagnosed AMD and dementia using a population-based dataset in Taiwan.Data for this case-control study were retrospectively collected from the Taiwan National Health Insurance Research Database. We identified 13,402 subjects who had a diagnosis of dementia as cases, and 40,206 subjects without dementia as controls. A conditional logistic regression was used to examine the association of dementia with previously diagnosed neovascular AMD.We found that of the study sample of 53,608 subjects, 1.01% had previously diagnosed neovascular AMD, 1.35% and 0.90% for cases and the controls, respectively (p