학술논문
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants
Document Type
article
Author
Lam C. Tsoi; Philip E. Stuart; Chao Tian; Johann E. Gudjonsson; Sayantan Das; Matthew Zawistowski; Eva Ellinghaus; Jonathan N. Barker; Vinod Chandran; Nick Dand; Kristina Callis Duffin; Charlotta Enerbäck; Tõnu Esko; Andre Franke; Dafna D. Gladman; Per Hoffmann; Külli Kingo; Sulev Kõks; Gerald G. Krueger; Henry W. Lim; Andres Metspalu; Ulrich Mrowietz; Sören Mucha; Proton Rahman; Andre Reis; Trilokraj Tejasvi; Richard Trembath; John J. Voorhees; Stephan Weidinger; Michael Weichenthal; Xiaoquan Wen; Nicholas Eriksson; Hyun M. Kang; David A. Hinds; Rajan P. Nair; Gonçalo R. Abecasis; James T Elder
Source
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Psoriasis is an immune-mediated skin disease with a complex genetic architecture. Here, Elder and colleagues identify 16 novel psoriasis susceptibility loci using GWAS meta-analysis with a combined effective sample size of over 39,000 individuals.