학술논문
Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom
Document Type
article
Author
Sarah R. Smith; Chris L. Dupont; James K. McCarthy; Jared T. Broddrick; Miroslav Oborník; Aleš Horák; Zoltán Füssy; Jaromír Cihlář; Sabrina Kleessen; Hong Zheng; John P. McCrow; Kim K. Hixson; Wagner L. Araújo; Adriano Nunes-Nesi; Alisdair Fernie; Zoran Nikoloski; Bernhard O. Palsson; Andrew E. Allen
Source
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
Here, using the diatom Phaeodactylum tricornutum as a model organism, the authors combine functional genomics, phylogenetics, and metabolic modeling to describe how diatoms might have functionally integrated nitrogen metabolism during evolution and how metabolic flux is regulated across cellular compartments