학술논문
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
Document Type
article
Author
Minako Imamura; Atsushi Takahashi; Toshimasa Yamauchi; Kazuo Hara; Kazuki Yasuda; Niels Grarup; Wei Zhao; Xu Wang; Alicia Huerta-Chagoya; Cheng Hu; Sanghoon Moon; Jirong Long; Soo Heon Kwak; Asif Rasheed; Richa Saxena; Ronald C. W. Ma; Yukinori Okada; Minoru Iwata; Jun Hosoe; Nobuhiro Shojima; Minaka Iwasaki; Hayato Fujita; Ken Suzuki; John Danesh; Torben Jørgensen; Marit E. Jørgensen; Daniel R. Witte; Ivan Brandslund; Cramer Christensen; Torben Hansen; Josep M. Mercader; Jason Flannick; Hortensia Moreno-Macías; Noël P. Burtt; Rong Zhang; Young Jin Kim; Wei Zheng; Jai Rup Singh; Claudia H. T. Tam; Hiroshi Hirose; Hiroshi Maegawa; Chikako Ito; Kohei Kaku; Hirotaka Watada; Yasushi Tanaka; Kazuyuki Tobe; Ryuzo Kawamori; Michiaki Kubo; Yoon Shin Cho; Juliana C. N. Chan; Dharambir Sanghera; Philippe Frossard; Kyong Soo Park; Xiao-Ou Shu; Bong-Jo Kim; Jose C. Florez; Teresa Tusié-Luna; Weiping Jia; E Shyong Tai; Oluf Pedersen; Danish Saleheen; Shiro Maeda; Takashi Kadowaki
Source
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Subject
Language
English
ISSN
2041-1723
Abstract
Here, Imamuraet al. conduct meta-analysis of genome-wide association studies to identify novel susceptibility loci for type 2 diabetes (T2D) in the Japanese population. By doing so, this study shows that both ethnicity-specific and ethnically-shared genetic loci can contribute to T2D risk.