학술논문
Candidate Plasma Biomarkers to Detect Anthracycline‐Related Cardiomyopathy in Childhood Cancer Survivors: A Case Control Study in the Dutch Childhood Cancer Survivor Study
Document Type
article
Author
Jan M. Leerink; Elizabeth A. M. Feijen; Perry D. Moerland; Esmee C. de Baat; Remy Merkx; Helena J. H. van der Pal; Wim J. E. Tissing; Marloes Louwerens; Marry M. van den Heuvel‐Eibrink; A. Birgitta Versluys; Folkert W. Asselbergs; Arjan Sammani; Arco J. Teske; Elvira C. van Dalen; Margriet van der Heiden‐van der Loo; Eline van Dulmen‐den Broeder; Andrica C. H. de Vries; Livia Kapusta; Jacqueline Loonen; Yigal M. Pinto; Leontien C. M. Kremer; Annelies M. C. Mavinkurve‐Groothuis; Wouter E. M. Kok
Source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 14 (2022)
Subject
Language
English
ISSN
2047-9980
Abstract
Background Plasma biomarkers may aid in the detection of anthracycline‐related cardiomyopathy (ACMP). However, the currently available biomarkers have limited diagnostic value in long‐term childhood cancer survivors. This study sought to identify diagnostic plasma biomarkers for ACMP in childhood cancer survivors. Methods and Results We measured 275 plasma proteins in 28 ACMP cases with left ventricular ejection fraction