학술논문
Chronic kidney disease, atherosclerotic plaque characteristics on carotid magnetic resonance imaging, and cardiovascular outcomes
Document Type
article
Author
Srinivasan Beddhu; Robert E. Boucher; Jie Sun; Niranjan Balu; Michel Chonchol; Sankar Navaneethan; Glenn M. Chertow; Raymond Townsend; William Haley; Alfred K. Cheung; Molly B. Conroy; Dominic S. Raj; Dongxiang Xu; Thomas George; Reem Yunis; Guo Wei; Gador Canton; Jeffrey Bates; Jing Chen; Vasilios Papademetriou; Henry Punzi; Alan Wiggers; Jackson T. Wright; Tom Greene; Chun Yuan
Source
BMC Nephrology, Vol 22, Iss 1, Pp 1-10 (2021)
Subject
Language
English
ISSN
1471-2369
Abstract
Abstract Background It is unclear whether faster progression of atherosclerosis explains the higher risk of cardiovascular events in CKD. The objectives of this study were to 1. Characterize the associations of CKD with presence and morphology of atherosclerotic plaques on carotid magnetic resonance imaging (MRI) and 2. Examine the associations of baseline CKD and carotid atherosclerotic plaques with subsequent cardiovascular events. Methods In a subgroup (N = 465) of Systolic Blood Pressure Intervention Trial. (SPRINT) participants, we measured carotid plaque presence and morphology at baseline and after 30-months with MRI. We examined the associations of CKD (baseline eGFR