학술논문
Rare germline copy number variants (CNVs) and breast cancer risk
Document Type
article
Author
Joe Dennis; Jonathan P. Tyrer; Logan C. Walker; Kyriaki Michailidou; Leila Dorling; Manjeet K. Bolla; Qin Wang; Thomas U. Ahearn; Irene L. Andrulis; Hoda Anton-Culver; Natalia N. Antonenkova; Volker Arndt; Kristan J. Aronson; Laura E. Beane Freeman; Matthias W. Beckmann; Sabine Behrens; Javier Benitez; Marina Bermisheva; Natalia V. Bogdanova; Stig E. Bojesen; Hermann Brenner; Jose E. Castelao; Jenny Chang-Claude; Georgia Chenevix-Trench; Christine L. Clarke; NBCS Collaborators; J. Margriet Collée; CTS Consortium; Fergus J. Couch; Angela Cox; Simon S. Cross; Kamila Czene; Peter Devilee; Thilo Dörk; Laure Dossus; A. Heather Eliassen; Mikael Eriksson; D. Gareth Evans; Peter A. Fasching; Jonine Figueroa; Olivia Fletcher; Henrik Flyger; Lin Fritschi; Marike Gabrielson; Manuela Gago-Dominguez; Montserrat García-Closas; Graham G. Giles; Anna González-Neira; Pascal Guénel; Eric Hahnen; Christopher A. Haiman; Per Hall; Antoinette Hollestelle; Reiner Hoppe; John L. Hopper; Anthony Howell; ABCTB Investigators; kConFab/AOCS Investigators; Agnes Jager; Anna Jakubowska; Esther M. John; Nichola Johnson; Michael E. Jones; Audrey Jung; Rudolf Kaaks; Renske Keeman; Elza Khusnutdinova; Cari M. Kitahara; Yon-Dschun Ko; Veli-Matti Kosma; Stella Koutros; Peter Kraft; Vessela N. Kristensen; Katerina Kubelka-Sabit; Allison W. Kurian; James V. Lacey; Diether Lambrechts; Nicole L. Larson; Martha Linet; Alicja Ogrodniczak; Arto Mannermaa; Siranoush Manoukian; Sara Margolin; Dimitrios Mavroudis; Roger L. Milne; Taru A. Muranen; Rachel A. Murphy; Heli Nevanlinna; Janet E. Olson; Håkan Olsson; Tjoung-Won Park-Simon; Charles M. Perou; Paolo Peterlongo; Dijana Plaseska-Karanfilska; Katri Pylkäs; Gad Rennert; Emmanouil Saloustros; Dale P. Sandler; Elinor J. Sawyer; Marjanka K. Schmidt; Rita K. Schmutzler; Rana Shibli; Ann Smeets; Penny Soucy; Melissa C. Southey; Anthony J. Swerdlow; Rulla M. Tamimi; Jack A. Taylor; Lauren R. Teras; Mary Beth Terry; Ian Tomlinson; Melissa A. Troester; Thérèse Truong; Celine M. Vachon; Camilla Wendt; Robert Winqvist; Alicja Wolk; Xiaohong R. Yang; Wei Zheng; Argyrios Ziogas; Jacques Simard; Alison M. Dunning; Paul D. P. Pharoah; Douglas F. Easton
Source
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
Dennis et al. investigate potential breast cancer associations with rare germline copy number variants (CNVs) by conducting a genome-wide analysis in a large breast cancer case-control dataset. The authors detected associations with exonic deletions in established breast cancer susceptibility genes and suggestive associations for a number of non-coding CNVs.