학술논문
HLA alleles, disease severity, and age associate with T-cell responses following infection with SARS-CoV-2
Document Type
article
Author
Thorunn A. Olafsdottir; Kristbjorg Bjarnadottir; Gudmundur L. Norddahl; Gisli H. Halldorsson; Pall Melsted; Kristbjorg Gunnarsdottir; Erna Ivarsdottir; Thorhildur Olafsdottir; Asgeir O. Arnthorsson; Fannar Theodors; Elias Eythorsson; Dadi Helgason; Hannes P. Eggertsson; Gisli Masson; Sólveig Bjarnadottir; Saedis Saevarsdottir; Hrafnhildur L. Runolfsdottir; Isleifur Olafsson; Jona Saemundsdottir; Martin I. Sigurdsson; Ragnar F. Ingvarsson; Runolfur Palsson; Gudmundur Thorgeirsson; Bjarni V. Halldorsson; Hilma Holm; Mar Kristjansson; Patrick Sulem; Unnur Thorsteinsdottir; Ingileif Jonsdottir; Daniel F. Gudbjartsson; Kari Stefansson
Source
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
A study of 768 convalescent SARS CoV-2-infected and 500 uninfected Icelanders reveals broad and stable T-cell responses 3-8 months from infection. HLA alleles, disease severity, and age contribute to the heterogeneity of cellular immunity.