학술논문
Project profile: a multicenter study on breast cancer in young women in Latin America (PRECAMA study)
Document Type
article
Author
Source
Salud Pública de México, Vol 61, Iss 5, sep-oct, Pp 601-608 (2019)
Subject
Language
English
Spanish; Castilian
Spanish; Castilian
ISSN
0036-3634
Abstract
Objective. To describe the rationale and the methodology of a multicenter project to study the etiology of breast cancer in young Latin American women. Materials and methods. The International Agency for Research on Cancer has established an international collaborative population-based case-control study in four countries in Latin America: Chile, Colombia, Costa Rica, and Mexico (the PRECAMA study). Standardized methodologies were developed to collect information on reproductive variables, lifestyle, anthropometry, diet, clinical and pathological data, and biological specimens. The study will be extended to other countries in the region. Conclusion. PRECAMA is unique in its multidisciplinary approach that combines genetics, genomics, and metabolomics with lifestyle factors. The data generated through this project will be instrumental to identify major risk factors for molecular subtypes of breast cancer in young women, which will be important for prevention and targeted screening programs in Latin America.