학술논문
Total enzymatic synthesis of cis-α-irone from a simple carbon source
Document Type
article
Author
Source
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Retrosynthetic pathway design using promiscuous enzymes can provide a solution to the biosynthetic production of natural products. Here, the authors design a pathway for the production of cis-α-irone with a promiscuous methyltransferase using structure-guided enzyme engineering strategies.