학술논문
Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension
Document Type
article
Author
Alfredo Guillén-Del-Castillo; Manuel López Meseguer; Vicent Fonollosa-Pla; Berta Sáez Giménez; Dolores Colunga-Argüelles; Eva Revilla-López; Manuel Rubio-Rivas; Maria Jose Cristo Ropero; Ana Argibay; Joan Albert Barberá Mir; Xavier Pla Salas; Amaya Martínez Meñaca; Ana Belén Madroñero Vuelta; Antonio Lara Padrón; Luis Sáez Comet; Juan Antonio Domingo Morera; Cristina González-Echávarri; Teresa Mombiela; Norberto Ortego-Centeno; Manuela Marín González; Carles Tolosa-Vilella; Isabel Blanco; Pilar Escribano Subías; Carmen Pilar Simeón-Aznar; RESCLE Consortium; REHAP Consortium
Source
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 ± 20.6% vs 93.6 ± 20.6%, P