학술논문
Helicobacter pylori Diagnostic Tests Used in Europe: Results of over 34,000 Patients from the European Registry on Helicobacter pylori Management
Document Type
article
Author
Natalia García-Morales; Ángeles Pérez-Aísa; Giulia Fiorini; Bojan Tepes; Manuel Castro-Fernández; Alfredo Lucendo; Irina Voynovan; Luis Bujanda; Ana Garre; Luis Rodrigo; Samuel Jesús Martínez Domínguez; Maja Denkovski; Jose M. Huguet Malavés; Laimas Jonaitis; Renate Bumane; Oleg Zaytsev; Pilar Mata Romero; Jesús Barrio; Luis Fernández-Salazar; Aiman Silkanovna Sarsenbaeva; Inmaculada Ortiz Polo; Sergey Alekseenko; Ilaria Maria Saracino; Dino Vaira; Alma Keco-Huerga; Dmitry Bordin; Antonio Gasbarrini; Frode Lerang; Theodore Rokkas; Juozas Kupčinskas; Marcis Leja; Gulustan Babayeva; Ricardo Marcos Pinto; Ante Tonkić; Sinead Smith; Perminder Phull; Gyorgy M. Buzas; Halis Simsek; Doron Boltin; Oleksiy Gridnyev; Marino Venerito; Vladimir Milivojevic; Núria Torà; Anna Cano-Català; Leticia Moreira; Olga P. Nyssen; Francis Mégraud; Colm O’Morain; Javier P. Gisbert; Ignasi Puig; on behalf of Hp-EuReg Investigators
Source
Journal of Clinical Medicine, Vol 12, Iss 13, p 4363 (2023)
Subject
Language
English
ISSN
2077-0383
Abstract
Background and aims: Several methods are available to diagnose Helicobacter pylori infection. Our objective was to evaluate the tests used for both the initial diagnosis and the confirmation of eradication after treatment in Europe. Methods: The European Registry on the management of Helicobacter pylori infection is an international, multicentre, prospective, non-interventional registry aiming to evaluate the management of Helicobacter pylori-infected patients in Europe. Countries with at least 100 cases registered from June 2013 to April 2021, and with a validated diagnostic method were analysed. Data were quality reviewed. Results: A total of 34,920 adult patients from 20 countries were included (mean age 51 years; 61% women). To establish the initial diagnosis, invasive tests were performed in 19,801 (71%) patients, non-invasive in 11,369 (41%), and both in 3437 (12%). The most frequent were histology (n = 11,885; 43%), a rapid urease test (n = 10,636; 38%) and an urea breath test (n = 7577; 27%). According to the age, invasive tests were indicated in 11,179 (77%) ≥50 years, and in 8603 (65%)