학술논문

MICROBIOME ANALYSIS IN PATIENTS WITH PSORIASIS
Document Type
article
Source
Romanian Medical Journal, Vol 66, Iss 4, Pp 346-352 (2019)
Subject
psoriasis
microbiome
next generation sequencing
Medicine (General)
R5-920
Surgery
RD1-811
Language
English
ISSN
1220-5478
2069-606X
Abstract
Psoriasis is a skin condition that occurs as a result of the interaction between predisposing genetic factors, immunological factors and external triggers. Studies have highlighted the important role played by Staphylococcus aureus or Streptococcus pyogenes in inducing, maintaining or exacerbating psoriasis lesions. Thus, the study of skin microbe in patients with psoriasis is considered to be extremely important and complementary to genetic and immunological research. New advances in new generation sequencing technologies allow for a better understanding of genetic mechanisms alteration in psoriasis. Studies performed so far show variable results, apparently due to the associated limitations, which imply that a standardized protocol for the sampling and processing of analyzed samples is a priority measure.