학술논문
Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits
Document Type
article
Author
Source
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Subject
Language
English
ISSN
2041-1723
66847168
66847168
Abstract
Isolated populations can provide useful information on low-frequency variants for dissecting genetic architecture of complex traits. Here, Zeggini and colleagues show enrichment of rare and low-frequency variants and 8 novel low-frequency variant signals for cardiometabolic traits in two Greek isolated populations