학술논문
Systematic analysis of protein turnover in primary cells
Document Type
article
Author
Source
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
The proteome-wide characterization of proteostasis depends on robust approaches to determine protein half-lives. Here, the authors improve the accuracy and precision of mass spectrometry-based quantification, enabling reliable protein half-life determination in several non-dividing cell types.