학술논문
Association of demographics, HCV co‐infection, HIV‐1 subtypes and genetic clustering with late HIV diagnosis: a retrospective analysis from the Japanese Drug Resistance HIV‐1 Surveillance Network
Document Type
article
Author
Machiko Otani; Teiichiro Shiino; Atsuko Hachiya; Hiroyuki Gatanaga; Dai Watanabe; Rumi Minami; Masako Nishizawa; Takanori Teshima; Shigeru Yoshida; Toshihiro Ito; Tsunefusa Hayashida; Michiko Koga; Mami Nagashima; Kenji Sadamasu; Makiko Kondo; Shingo Kato; Shunsuke Uno; Toshibumi Taniguchi; Hidetoshi Igari; Sei Samukawa; Hideaki Nakajima; Yusuke Yoshino; Masahide Horiba; Hiroshi Moro; Tamayo Watanabe; Mayumi Imahashi; Yoshiyuki Yokomaku; Haruyo Mori; Teruhisa Fujii; Kiyonori Takada; Asako Nakamura; Hideta Nakamura; Masao Tateyama; Shuzo Matsushita; Kazuhisa Yoshimura; Wataru Sugiura; Tetsuro Matano; Tadashi Kikuchi; Japanese Drug Resistance HIV‐1 Surveillance Network
Source
Journal of the International AIDS Society, Vol 26, Iss 5, Pp n/a-n/a (2023)
Subject
Language
English
ISSN
1758-2652
Abstract
Abstract Introduction Late diagnosis of the human immunodeficiency virus (HIV) is a major concern epidemiologically, socially and for national healthcare systems. Although the association of certain demographics with late HIV diagnosis has been reported in several studies, the association of other factors, including clinical and phylogenetic factors, remains unclear. In the present study, we conducted a nationwide analysis to explore the association of demographics, clinical factors, HIV‐1 subtypes/circulating recombinant form (CRFs) and genetic clustering with late HIV diagnosis in Japan, where new infections mainly occur among young men who have sex with men (MSM) in urban areas. Methods Anonymized data on demographics, clinical factors and HIV genetic sequences from 39.8% of people newly diagnosed with HIV in Japan were collected by the Japanese Drug Resistance HIV‐1 Surveillance Network from 2003 to 2019. Factors associated with late HIV diagnosis (defined as HIV diagnosis with a CD4 count