학술논문

Immunological changes in a cohort of COVID-19 survivors: Mansoura University experience [version 2; peer review: 2 approved]
Document Type
article
Source
F1000Research, Vol 12 (2023)
Subject
Post COVID immunity
COVID-19
IgM
IgG
antibodies
diabetes
eng
Medicine
Science
Language
English
ISSN
2046-1402
Abstract
Background: COVID-19 is a global pandemic that has affected millions of people all over the world since 2019. Infection with COVID-19 initiates a humoral immune response that produces antibodies against specific viral antigens, which in turn is supposed to provide immunity against reinfection for a period of time. The aim of this research was to study the kinetics of IgM and IgG antibodies against SARS-CoV-2. Methods: One hundred and seventeen post-COVID-19 participants were enrolled in the study. Qualitative assessment of IgM and IgG antibodies over six months (three visits) post recovery was conducted. Results: The current study revealed a significant reduction in IgM and IgG titers between the first and second visits (p