학술논문
A multi-country study on the impact of sex and age on oral features of COVID-19 infection in adolescents and young adults
Document Type
article
Author
Heba Jafar Sabbagh; Wafaa Abdelaziz; Maryam Quritum; Rana Abdullah Alamoudi; Nada Abu Bakr AlKhateeb; Joud Abourdan; Nafeesa Qureshi; Shabnum Qureshi; Ahmed H. N. Hamoud; Nada Mahmoud; Ruba Odeh; Nuraldeen Maher Al-Khanati; Rawiah Jaber; Abdulrahman Loaie Balkhoyor; Mohammed Shabi; Morenike Oluwatoyin Folayan; Omolola Alade; Noha Gomaa; Raqiya Alnahdi; Nawal A. Mahmoud; Hanane El Wazziki; Manal Alnaas; Bahia Samodien; Rawa A. Mahmoud; Nour Abu Assab; Sherin Saad; Maha Mohamed Alsayad; Sondos G. Alhachim; Maha El Tantawi
Source
BMC Oral Health, Vol 22, Iss 1, Pp 1-6 (2022)
Subject
Language
English
ISSN
1472-6831
01984047
01984047
Abstract
Abstract Background Oral diseases are features of COVID-19 infection. There is, however, little known about oral diseases associated with COVID-19 in adolescents and young adults (AYA). Therefore, the aim of this study was to assess oral lesions’ association with COVID-19 infection in AYA; and to identify if sex and age will modify these associations. Methodology Data was collected for this cross-sectional study between August 2020 and January 2021 from 11-to-23 years old participants in 43-countries using an electronic validated questionnaire developed in five languages. Data collected included information on the dependent variables (the presence of oral conditions- gingival inflammation, dry mouth, change in taste and oral ulcers), independent variable (COVID-19 infection) and confounders (age, sex, history of medical problems and parents’ educational level). Multilevel binary logistic regression was used for analysis. Results Complete data were available for 7164 AYA, with 7.5% reporting a history of COVID-19 infection. A significantly higher percentage of participants with a history of COVID-19 infection than those without COVID-19 infection reported having dry mouth (10.6% vs 7.3%, AOR = 1.31) and taste changes (11.1% vs 2.7%, AOR = 4.11). There was a significant effect modification in the association between COVID-19 infection and the presence of dry mouth and change in taste by age and sex (P = 0.02 and