학술논문
Cognitive Functions in Epileptic Patients on Lamotrigine and Other Antiepileptic Drugs
Document Type
article
Author
Source
Journal of Mazandaran University of Medical Sciences, Vol 29, Iss 172, Pp 34-42 (2019)
Subject
Language
English
Persian
Persian
ISSN
1735-9260
1735-9279
1735-9279
Abstract
Background and purpose: Anti-epileptic drugs (AEDs) can affect cognitive functions. The purpose of this study was to investigate the effects of lamotrigine (LT) on cognitive functions of patients with epilepsy. Materials and methods: A study with retrospective cohort design was carried out in which we assessed cognitive functions of 20 IGE patients attending Sari Bu Ali Hospital, and 12 healthy subjects. The control group was matched for age, sex, and educational level. Standardized neuropsychological tests were used to evaluate cognitive functions. The study was analyzed applying one-way ANOVA and Tukey Test in SPSS. Results: Compared with the control group, LT group showed poor performance in Stroop test and verbal fluency test-semantic test (P