학술논문

Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities
Document Type
article
Source
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-15 (2022)
Subject
SARS-CoV-2
COPD
Asthma
Stem cells
Regenerative medicine
Medicine
Cytology
QH573-671
Language
English
ISSN
1478-811X
Abstract
Abstract Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been growing swiftly worldwide. Patients with background chronic pulmonary inflammations such as asthma or chronic obstructive pulmonary diseases (COPD) are likely to be infected with this virus. Of note, there is an argument that COVID-19 can remain with serious complications like fibrosis or other pathological changes in the pulmonary tissue of patients with chronic diseases. Along with conventional medications, regenerative medicine, and cell-based therapy could be alternative approaches to compensate for organ loss or restore injured sites using different stem cell types. Owing to unique differentiation capacity and paracrine activity, these cells can accelerate the healing procedure. In this review article, we have tried to scrutinize different reports related to the harmful effects of SARS-CoV-2 on patients with asthma and COPD, as well as the possible therapeutic effects of stem cells in the alleviation of post-COVID-19 complications. Video abstract