학술논문

Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS
Document Type
article
Source
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Combinatorial Gene×Gene×Environment CRISPR screen targeting human SLC25 transporter family enables the identification of SLC25A39 in mitochondrial glutathione import and its coordination with mitochondrial iron import in supporting OXPHOS.